E-MEXP-3098 - Gene expression profiling of mouse chronic intestinal inflammation
Released on 13 May 2013, last updated on 3 September 2013
Trichuris muris (T. muris) induces chronic colitis in susceptible mouse strains with clinical, histological, and immunological homology to human Crohn’s disease. Gene expression profiling was performed on colon tissue of resistant (BALB/c) and susceptible (AKR) mice following T. muris infection.
transcription profiling by array, co-expression, disease state, in vivo, strain or line
Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation. Levison SE, Fisher P, Hankinson J, Zeef L, Eyre S, Ollier WE, McLaughlin JT, Brass A, Grencis RK, Pennock JL. BMC Genomics 14:127 (2013), Europe PMC 23442222