E-MEXP-23 - Transcription profiling of mouse aorta and vSMCs response to dioxin
Released on 29 October 2003, last updated on 2 May 2014
We compared the global gene expression profiles of C57BL/6 mice aortas with the profiles of cultured vascular smooth muscle cells (vSMC) from the same mice, and determined whether gene responses to dioxin exposure in the vSMCs would be predictive of responses in the aorta.
transcription profiling by array, cell type comparison, growth condition
Maureen A Sartor <email@example.com>, Alvaro Puga, Craig R Tomlinson, Kevin J Kerzee, Mario Medvedovic, Ming-ya Huang, Stuart C Baxter, Yu-Dan Wei
Gene expression profiles of mouse aorta and cultured vascular smooth muscle cells are widely different, yet show common responses to dioxin exposure. Alvaro Puga; Maureen Sartor; Ming-ya Huang; Kevin Kerzee; Yu-Dan Wei; Craig Tomlinson; Stuart Baxter; Mario Medvedovic.