E-MEXP-199 - Transcription profiling of response of human Hep3B (Hepatoma cells) following rAdTAp63 or rAdTAp53 transfer

Status
Submitted on 16 October 2004, released on 1 June 2005, last updated on 2 May 2014
Organism
Homo sapiens
Samples (5)
Array (1)
Protocols (6)
Description
We performed microarray analyses to examine whether TAp63alpha is able to induce the expression of several pro-apoptotic and immunosystem related genes in Hep3B (hepatoma) cells. We investigated the downstream mechanisms by which TAp53 elicits apoptosis.
Experiment types
transcription profiling by array, development or differentiation, time series
Contact
Citation
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. Gressner O, Schilling T, Lorenz K, Schulze Schleithoff E, Koch A, Schulze-Bergkamen H, Lena AM, Candi E, Terrinoni A, Catani MV, Oren M, Melino G, Krammer PH, Stremmel W, Müller M. EMBO J 24(13):2458-2471 (2005), Europe PMC 15944736
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MEXP-199.idf.txt
Sample and data relationshipE-MEXP-199.sdrf.txt
Raw data (1)E-MEXP-199.raw.1.zip
Array designA-RZPD-21.adf.txt
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