E-MEXP-1496 - RNAi knock down of AURKA in human neuroblastoma IMR-32 cells
Submitted on 29 February 2008, released on 1 June 2008, last updated on 10 June 2011
IMR-32 cells were infected either with control-shRNA or one of two different AURKA-shRNA vectors to identify genes regulated after AURKA knockdown.
RNAi profiling by array, cellular modification, co-expression, dye swap, in vitro
Stabilization of N-Myc is a critical function of Aurora-A in human neuroblastoma. Tobias Otto, Sebastian Horn, Markus Brockmann, Ursula Eilers, Lars Schüttrumpf, Nikita Popov, Anna Marie Kenney, Johannes Schulte, Roderick Beijersbergen, Holger Christiansen, Bernd Berwanger and Martin Eilers. Cancer Cell (2008)