E-MEXP-1482 - Transcription profiling of human chronic lymphocytic leukemia samples and pRS-15/16 transfected MEG01 cell lines to identify MiR-15a and miR-16-1 cluster function in human leukemia
Submitted on 29 February 2008, released on 1 June 2008, last updated on 27 March 2012
Two samples obtained from the MEG01 cell line transfected with pRS-15/16 and pRS-E vector, each one in triplicate, and 16 CLL samples were analyzed by microarray using Human Genome U133A Plus 2.0 GeneChip arrays (Affymetrix).
transcription profiling by array, co-expression, replicate, transcript identification
MiR-15a and miR-16-1 cluster functions in human leukemia. Calin GA, Cimmino A, Fabbri M, Ferracin M, Wojcik SE, Shimizu M, Taccioli C, Zanesi N, Garzon R, Aqeilan RI, Alder H, Volinia S, Rassenti L, Liu X, Liu CG, Kipps TJ, Negrini M, Croce CM. Proc Natl Acad Sci U S A 105(13):5166-71 (2008)