E-MEXP-1048 - Transcription profiling of mouse cerebella from pups exposed to PTU to induce hypothyroidism
Released on 2 May 2008, last updated on 2 May 2014
Pregnant dams were treated with 0.1% or 0.04% 6-propyl-2-thiouracil (PTU) in drinking water continuously from day 13 post conception until weaning to produce hypothyroid pups. Cerebella were collected from vehicle and 0.1% PTU treated pups at post-natal day (PND) 15 and mRNA from these was subjected to microarray analysis using Agilent high-density oligonucleotide chips.
transcription profiling by array, co-expression, compound treatment, in vivo
Molecular insight into the effects of hypothyroidism.