E-MEXP-1014 - Transcription profiling by array of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Released on 1 April 2008, last updated on 14 August 2014
Several studies indicate that omega (n)-3 fatty acids may have a potential in the prevention and treatment of cancer. In this study the colon cancer cell lines SW480 and SW620 were treated with the n-3 PUFA DHA (Docosahexaenoic acid) for 3 different time points (12, 24 and 48h). The experiments were performed in three independent replicates (1-3), RNA isolated and used for Affymetrix gene expression analysis.
transcription profiling by array, co-expression, compound treatment, strain or line, time series
DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis. Jakobsen, Caroline Hild; Storvold, Gro Leite; Bremseth, Hilde; Follestad, Turid; Sand, Kristin; Mack, Merete; Olsen, Karina Standahl; Lundemo, Anne Goril; Iversen, Jens Gustav; Krokan, Hans Einar; Schonberg, Svanhild Arentz. , Europe PMC 18566476