E-GEOD-990 - Transcription profiling of C2C12 myoblasts induced to differentiate in vitro over a 12 day time series to identify novel genes involved in myogenic differentiation.
Submitted on 22 January 2004, released on 13 December 2007, last updated on 27 March 2012
In this study, Affymetrix MG_U74Av2 and MG_U74Cv2 GeneChips were used to analyze gene expression over a 12 day time course in C2C12 myoblasts induced to differentiate in vitro. Triplicate cultures were studied during cell proliferation (days -2 and -1), at cell cycle withdrawal (day 0) and during myogenic fusion and maturation of multinucleated myotubes (days 2, 4, 6, 8, 10). The manuscript associated to this work is Tomczak et al., FASEB J., 2003 Dec 19. Additionally, the supplementary data can be found on our homepage at http://www.chb-genomics.org/beggslab/
transcription profiling by array, co-expression, development or differentiation, time series
Expression profiling and identification of novel genes involved in myogenic differentiation. Kinga K Tomczak, Voichita D Marinescu, Marco F Ramoni, Despina Sanoudou, Federica Montanaro, Mei Han, Louis M Kunkel, Isaac S Kohane, Alan H Beggs. FASEB J 18(2):403-5 (2004)