E-GEOD-9650 - Transcription profiling of mouse naive, effector, memory and exhausted virus-specific CD8 T cells after chronic viral infection

Status
Released on 16 June 2008, last updated on 12 October 2011
Organism
Mus musculus
Samples (25)
Arrays (3)
Protocols (10)
Description
CD8 T cells normally differentiate from resting naïve T cells into function effector and then memory CD8 T cells following acute infections. During chronic viral infections, however, virus-specific CD8 T cells often become exhausted. We used microarrays to examine the gene expression differences between naive, effector, memory and exhausted virus-specific CD8 T cells following lymphocytic choriomeningitis virus infection. Experiment Overall Design: Three or four independent samples were sorted by flow cytometry for each cell type (naive, effector, memory and exhausted) virus-specific CD8 T cells. RNA was extracted and hybridized to Affymetrix microarrays.
Experiment types
transcription profiling by array, unknown experiment type
Contact
Shruti Subramaniam
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-9650.idf.txt
Sample and data relationshipE-GEOD-9650.sdrf.txt
Raw data (1)E-GEOD-9650.raw.1.zip
Processed data (1)E-GEOD-9650.processed.1.zip
Array designsA-AFFY-6.adf.txt, A-AFFY-7.adf.txt, A-AFFY-8.adf.txt
Links