E-GEOD-769 - Transcription profiling of pancreases of cystic fibrosis mouse with a genotype of gastrin+/-, CFTR-/- to study the gene expression patterns in cystic fibrosis.

Status
Submitted on 22 October 2003, released on 15 December 2007, last updated on 27 March 2012
Organism
Mus musculus
Samples (6)
Array (1)
Protocols (2)
Description
Total RNA was prepared using TRIzol reagent from the pancreata of eight week old male mice. The genotypes were Control: gastrin+/-, CFTR+/+; and CF: gastrin+/-, CFTR-/-. All mice were on 95% black6, 5% 129Sv background. Mice were fed Peptamen from age 10 days to prevent intestinal obstruction.
Experiment types
transcription profiling by array, co-expression, disease state, individual genetic characteristics
Contact
Citation
Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreas. Simran Kaur, Oxana Norkina, Donna Ziemer, Linda C Samuelson, Robert C De Lisle. Am J Physiol Gastrointest Liver Physiol 287(2):G480-90 (2004)
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-769.idf.txt
Sample and data relationshipE-GEOD-769.sdrf.txt
Raw data (1)E-GEOD-769.raw.1.zip
Processed data (1)E-GEOD-769.processed.1.zip
Array designA-AFFY-6.adf.txt
R ExpressionSetE-GEOD-769.eSet.r
Links