E-GEOD-7669 - Transcription profiling of human synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients
Submitted on 30 April 2007, released on 28 April 2009, last updated on 2 May 2014
mRNA expression levels in synovial fibroblasts in 6 rheumatoid arthritis patients versus 6 osteoarthritis patients. Experiment Overall Design: Synovial tissue was obtained from open joint replacement surgery or Experiment Overall Design: arthroscopic synovectomy. Patients with RA or OA (n = 6 each for gene expression analysis and further patients for validation experiments) were classified according to the ACR criteria.
transcription profiling by array, disease state
Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts. Dirk Pohlers, Andreas Beyer, Dirk Koczan, Thomas Wilhelm, Hans-Jürgen Thiesen, Raimund W Kinne. Arthritis Res Ther 9(3):R59 (2007)