E-GEOD-7407 - Transcription profiling of mouse transgenics with cardiac specific overexpression of Sirt1 (Tg-Sirt1) and non-transgenic (NTg) control littermate at 3 months of age

Status
Submitted on 29 March 2007, released on 15 June 2008, last updated on 27 March 2012
Organism
Mus musculus
Samples (4)
Array (1)
Protocols (4)
Description
We harvested the heart from transgenic mice with cardiac specific overexpression of Sirt1 (Tg-Sirt1) and non-transgenic (NTg) control littermate at 3 months of age and then microarray analyses were conducted. Experiment Overall Design: Two transgenic mice and two wild type mice were used.
Experiment types
transcription profiling by array, genetic modification
Contact
Citation
Sirt1 regulates aging and resistance to oxidative stress in the heart. Ralph R Alcendor, Shumin Gao, Peiyong Zhai, Daniela Zablocki, Eric Holle, Xianzhong Yu, Bin Tian, Thomas Wagner, Stephen F Vatner, Junichi Sadoshima. Circ Res 100(10):1512-21 (2007)
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-7407.idf.txt
Sample and data relationshipE-GEOD-7407.sdrf.txt
Raw data (1)E-GEOD-7407.raw.1.zip
Processed data (1)E-GEOD-7407.processed.1.zip
Array designA-AFFY-45.adf.txt
R ExpressionSetE-GEOD-7407.eSet.r
Links