E-GEOD-7355 - Transcription profiling of human HUVEC cells infected with Candida
Submitted on 23 March 2007, released on 15 June 2008, last updated on 2 May 2014
Using oligonucleotide microarray analysis, we identified 56 genes that were transcriptionally up-regulated and 69 that were suppressed upon exposure of endothelial cells to C. albicans. Among the regulated genes those attributed to the categories ‘chemotaxis’, ‘signaling’, and ‘transcription and translation’ were remarkably overrepresented. Experiment Overall Design: We performed 4 independent experiments comparing the expression profiles of untreated HUVEC monolayer with those of candida-infected HUVEC monolayer.
transcription profiling by array, unknown experiment type