E-GEOD-6563 - Transcription profiling of C. elegans daf-19(+) and daf-19(-) mutants
Submitted on 18 December 2006, released on 14 June 2008, last updated on 27 March 2012
By screening for genes possessing canonical X-box sequences in promoters of three Caenorhabditis species, namely C. elegans, C. briggsae and C. remanei, we identified 93 genes (including known X-box regulated genes) that encode putative components of ciliated neurons in C. elegans and are subject to the same regulatory control. For many of these genes, restricted anatomical expression in ciliated cells was confirmed, and control of transcription by the ciliogenic DAF-19 RFX transcription factor was demonstrated by comparative transcriptional profiling of daf-19(+) and daf-19(-) animals. Experiment Overall Design: There 4 samples.
transcription profiling by array, unknown experiment type
Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Nansheng Chen, Allan Mah, Oliver E Blacque, Jeffrey Chu, Kiran Phgora, Mathieu W Bakhoum, C Rebecca Hunt Newbury, Jaswinder Khattra, Susanna Chan, Anne Go, Evgeni Efimenko, Robert Johnsen, Prasad Phirke, Peter Swoboda, Marco Marra, Donald G Moerman, Michel R Leroux, David L Baillie, Lincoln D Stein. Genome Biol 7(12):R126 (2006)