E-GEOD-56531 - Arid1a deletion in collaboration with Pten deletion leads to ovarian tumorigenesis in mouse

Status
Released on 5 April 2014, last updated on 3 June 2014
Organism
Mus musculus
Samples (9)
Array (1)
Protocols (5)
Description
Mice developed ovarian tumors after Arid1a and Pten double knockout. Gene expression profiles of 5 such ovarian tumors were compared with those of 4 normal ovaries. The differentially expressed genes were then used to investigate the similarity between the mouse ovarian tumors and major subtypes of human ovarian cancers. Total RNA obtained from the mouse ovarian tumors developing after Arid1a and Pten knockout compared to normal mouse ovaries.
Experiment type
transcription profiling by array 
Contacts
Ie-Ming Shih <geo@ncbi.nlm.nih.gov>, Bin Guan, Ren-Chin Wu, Tian-Li Wang, Yihong Wang, Yohan S Rahmanto, Zhong Wang
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-56531.idf.txt
Sample and data relationshipE-GEOD-56531.sdrf.txt
Processed data (1)E-GEOD-56531.processed.1.zip
Array designA-MEXP-1174.adf.txt
Links