E-GEOD-56465 - Comparison of haploid and diploid clones of KBM7 cancer cell line
Released on 10 April 2014, last updated on 3 June 2014
The series were performed to study the changes in gene expression upon diploidization of KBM7 cancer (CML) cell line. The line can exist either as a clone with 24 chromosomes (nearly haploid) or with 48 chromosomes (nearly diploid). Gene expression patterns are largely ploidy-independent, as suggested by this experiment Single cell derived clones of KBM7 cell line were grown. Included 7 haploid and 10 diploid clones, each with 2 independent total RNA extraction/microarray run. Also included peripheral blood mononuclear cells (PBMC) samples for comparison purposes.
transcription profiling by array
Yan Feng, Yegor Smurnyy