E-GEOD-5297 - Transcription profiling of mouse overexpressing MHC-I after endurance training

Status
Submitted on 12 July 2006, released on 13 June 2008, last updated on 27 March 2012
Organism
Mus musculus
Samples (20)
Array (1)
Description
Myosine heavy chain I was overexpressed in mouse skeletal muscle. The transgenic mice, as well as the wild type mice, were endurance trained on treadmill for 5 days/week over 8 weeks at 80% peak aerobic capacity in comparison with untrained mice. The gene expression profiles of the skeletal muscles from wild-type trained (WTT) and untrained (WTUT), and transgenic trained (TGT) and untrained (TGUT) were measured using Affymetrix Mouse430A 2.0 GeneChips. Experiment Overall Design: There were 5 WTT, 5 WTUT, 5 TGT, and 5 TGUT mice used in microarray studies.
Experiment types
transcription profiling by array, unknown experiment type
Contact
Citation
Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function. Lisa S Chow, Laura J Greenlund, Yan W Asmann, Kevin R Short, Shelly K McCrady, James A Levine, K Sreekumaran Nair. J Appl Physiol 102(3):1078-89 (2007)
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-5297.idf.txt
Sample and data relationshipE-GEOD-5297.sdrf.txt
Processed data (1)E-GEOD-5297.processed.1.zip
Array designA-AFFY-45.adf.txt
Links