E-GEOD-5297 - Transcription profiling of mouse overexpressing MHC-I after endurance training
Submitted on 12 July 2006, released on 13 June 2008, last updated on 27 March 2012
Myosine heavy chain I was overexpressed in mouse skeletal muscle. The transgenic mice, as well as the wild type mice, were endurance trained on treadmill for 5 days/week over 8 weeks at 80% peak aerobic capacity in comparison with untrained mice. The gene expression profiles of the skeletal muscles from wild-type trained (WTT) and untrained (WTUT), and transgenic trained (TGT) and untrained (TGUT) were measured using Affymetrix Mouse430A 2.0 GeneChips. Experiment Overall Design: There were 5 WTT, 5 WTUT, 5 TGT, and 5 TGUT mice used in microarray studies.
transcription profiling by array, unknown experiment type
Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function. Lisa S Chow, Laura J Greenlund, Yan W Asmann, Kevin R Short, Shelly K McCrady, James A Levine, K Sreekumaran Nair. J Appl Physiol 102(3):1078-89 (2007)