E-GEOD-51698 - The effect of imatinib therapy on tumor associated macrophages (TAMs) in murine gastrointestinal stromal tumor (GIST)

Status
Released on 20 November 2013, last updated on 3 June 2014
Organism
Mus musculus
Samples (4)
Array (1)
Protocols (7)
Description
The gene expression profile of TAMs sorted from vehicle control tumors in GIST mice (Sommer et al, PNAS 2003) was compared to TAMs sorted from mice after 2 weeks of imatinib therapy The Affymetrix Mouse Genome 430A 2.0 platform was used Each treatment group had 8 mice. After 2 weeks of treatment, mice were sacrificed and tumors digested with collagenase. TAMs were then FACS sorted and pooled by group. Pooled groups were run in duplicate for the gene expression array.
Experiment type
transcription profiling by array 
Contacts
Jeffrey Zhao <zhaoy@mskcc.org>, Adrian M Seifert, Benjamin L Green, Cristina R Antonescu, Eric C Sorenson, Ferdinand Rossi, Jonathan B Greer, Lee M Ocuin, Megan H Crawley, Michael J Cavnar, Noah A Cohen, Peter Besmer, Rachel Popow, Ronald P DeMatteo, Shan Zeng, Teresa S Kim, Vinod P Balachandran
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-51698.idf.txt
Sample and data relationshipE-GEOD-51698.sdrf.txt
Raw data (1)E-GEOD-51698.raw.1.zip
Processed data (1)E-GEOD-51698.processed.1.zip
Array designA-AFFY-36.adf.txt
Links