E-GEOD-51538 - SNP array analysis of single cell genomes

Status
Released on 4 December 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (101)
Array (1)
Protocols (6)
Description
This study (McConnell, et al. Science 2012) used both SNP array and sequencing data to examine copy number variation in neuronal genomes. Encolsed here are the SNP Array data from the 42 fibroblasts, 19 human induced pluripotent stem cell (hiPSC)-derived neural progenitor cells (NPCs), and 40 hiPSC-derived neurons that were reported in the manuscript. Copy number analysis was performed on .CEL files using Partek Genomics Suite with a custom single cell reference file.
Experiment types
genotyping by array, comparative genomic hybridization by array 
Contacts
Michael J McConnell <mikemc@virginia.edu>, Chris Cowing-Zitron, Fred H Gage, Ira M Hall, Joris Vermeesch, Julia C Piper, Kristen J Brennand, Michael R Lindberg, Roger S Lasken, Svetlana Shumilina, Thierry Voet
Citation
Mosaic copy number variation in human neurons. McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH. , Europe PMC 24179226
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-51538.idf.txt
Sample and data relationshipE-GEOD-51538.sdrf.txt
Raw data (12)Click to browse raw data
Array designA-AFFY-107.adf.txt
Links