E-GEOD-5129 - Transcription profiling of mouse IL-18 knockouts vs. wild types treated with pressure overload to examine cardiac hypertrophy

Status
Submitted on 22 June 2006, released on 13 June 2008, last updated on 27 March 2012
Organism
Mus musculus
Samples (4)
Array (1)
Description
Pressure overload-induced cardiac hypertrophy was examined in IL-18 knockout and littermate control mice. Experiment Overall Design: 4 groups with RNA pooled from 5-6 per group. Role of IL-18 on gene expression in cardiac hypertrophy induced by pressure overload (transaortic constriction)
Experiment types
transcription profiling by array, individual genetic characteristics
Contact
Citation
Interleukin-18 knockout mice display maladaptive cardiac hypertrophy in response to pressure overload. James T Colston, William H Boylston, Marc D Feldman, Chris P Jenkinson, Sam D de la Rosa, Amanda Barton, Rodolfo J Trevino, Gregory L Freeman, Bysani Chandrasekar. Biochem Biophys Res Commun 354(2):552-8 (2007)
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-5129.idf.txt
Sample and data relationshipE-GEOD-5129.sdrf.txt
Processed data (1)E-GEOD-5129.processed.1.zip
Array designA-AFFY-36.adf.txt
Links