E-GEOD-51276 - mRNA microarray analysis on HepG2 cells exposed to amorphous Silica Nanoparticles (SiO2-NP)

Status
Released on 1 October 2013, last updated on 3 May 2014
Organism
Homo sapiens
Samples (2)
Array (1)
Protocols (8)
Description
In order to evaluate the identification of genes and pathways, the global gene expression profiles were assessed in response to amorphous Silica nanoparticles on Human hepatoma (HepG2) cells. We performed whole genome DNA microarray experiments using HepG2 cells exposed to for 24h. We used whole genome microarrays to screen for global changed in HepG2 transcription profiles and with subsequent quantitative analysis conducted on selected genes. 24h SiO2-NP (100 mg/L) exposed HepG2 cells were used for total RNA extraction and hybridization on Affymetrix microarrays.
Experiment type
transcription profiling by array 
Contacts
jinhee choi <jinhchoi@uos.ac.kr>, Jinhee Choi, Nivedita Chatterjee
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-51276.idf.txt
Sample and data relationshipE-GEOD-51276.sdrf.txt
Raw data (1)E-GEOD-51276.raw.1.zip
Processed data (1)E-GEOD-51276.processed.1.zip
Array designA-AFFY-141.adf.txt
Links