E-GEOD-51258 - ERG induced mesenchymal like gene signature

Status
Released on 19 October 2013, last updated on 28 October 2013
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (7)
Description
ERG overexpression was conducted in stably transfected K562 cell line with a tet-on inducible plasmid habouring ERG3. Prolonged induction of ERG (8 days) produced spindle cell shape changes whereas non-induced cells retained the round morphology. In oder to determine the genes responsible for inducing cell shape changes, a genome wide transcriptional screen was conducted. Three clones that potently induced ERG overexpression (8 days) with the corresponding non-induced cells were hybridized.
Experiment type
transcription profiling by array 
Contacts
Claudia D Baldus <claudia.baldus@charite.de>, Liliana H Mochmann, Martin Neumann, Verena Nowak, Wolf K Hofmann
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-51258.idf.txt
Sample and data relationshipE-GEOD-51258.sdrf.txt
Raw data (1)E-GEOD-51258.raw.1.zip
Processed data (1)E-GEOD-51258.processed.1.zip
Array designA-AFFY-44.adf.txt
Links