E-GEOD-51055 - Divergent Compensatory Responses to High Fat Diet Between C57BL6/J and C57BLKs/J Inbred Mouse Strains

Status
Released on 21 September 2013, last updated on 3 June 2014
Organism
Mus musculus
Samples (24)
Array (1)
Protocols (6)
Description
To assess whether changes in islet gene expression contribute to differences in phenotypes in response to high fat diet or tretament with pioglitazone, Agilent Whole Mouse Genome Oligo Microarrays were performed on RNA isolated from islets of 4 mice per each treatment group for discovery analysis of gene expression. Male 8 week-old BL6 and BLKS mice were fed normal chow (18% kcal from fat), HFD (42% kcal from fat), or HFD supplemented with the PPAR-γ agonist pioglitazone (PIO) (140 mg PIO/kg diet) for 16 weeks.
Experiment type
transcription profiling by array 
Contacts
Emily K Sims <eksims@iu.edu>, Carmella Evans Molina, Raghu Mirmira
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-51055.idf.txt
Sample and data relationshipE-GEOD-51055.sdrf.txt
Raw data (2)E-GEOD-51055.raw.1.zip, E-GEOD-51055.raw.2.zip
Processed data (1)E-GEOD-51055.processed.1.zip
Array designA-GEOD-13912.adf.txt
Links