E-GEOD-51037 - M. tuberculosis (Mtb) Produces Nitrite in Human Macrophages in Physiologic Oxygen to Impact Mycobacterial ATP Consumption and Gene Expression

Status
Released on 21 October 2013, last updated on 25 November 2013
Organism
Mycobacterium tuberculosis H37Rv
Samples (6)
Protocols (3)
Description
We sequenced mRNA from Mtb that had been treated with 5 mM nitrate or was untreated in standard 7H9/ADNaCl medium. This generated the first analysis of gene expression following mycobacterial nitrate respiration. Examination of mRNA levels in Mtb following nitrate respiration, which results in the production of nitrite.
Experiment type
RNA-seq of coding RNA 
Contacts
Carl Nathan <cnathan@med.cornell.edu>, Bussel A Cunningham, C Nathan, T Zhang
MINSEQE
Exp. designProtocolsFactorsProcessedSeq. reads
Files
Investigation descriptionE-GEOD-51037.idf.txt
Sample and data relationshipE-GEOD-51037.sdrf.txt
Links