E-GEOD-51030 - Gene expression analysis of human adipose-derived stem cells.

Status
Released on 21 September 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (1)
Array (1)
Protocols (7)
Description
Transcriptional activity was identified in all categories of genes expressed by ADSC, including collagens, ECM and basement membrane constituents, adhesion molecules involved in cell-cell and cell-matrix interactions, and proteases involved in degradation of the ECM and their inhibitors. Importantly, it was observed that ADSC synthesize and secrete all three collagen VI chains, suggesting suitability of ADSC for collagen VI congenital muscular dytrophy treatment. We developed a procedure for isolation of human stem cells from adipose layer of neonatal foreskin skin. The adipose-derived stem cells (ADSC) were examined for expression of extracellular matrix (ECM) and related genes using gene expression array analysis.
Experiment type
transcription profiling by array 
Contacts
Olga Igoucheva, Sankar Addya, Vitali Alexeev
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-51030.idf.txt
Sample and data relationshipE-GEOD-51030.sdrf.txt
Raw data (1)E-GEOD-51030.raw.1.zip
Processed data (1)E-GEOD-51030.processed.1.zip
Array designA-GEOD-14550.adf.txt
Links