E-GEOD-49883 - Analysis of the DNA methylome and transcriptome in granulopoiesis reveal timed changes and dynamic enhancer methylation [expression]
Released on 29 April 2014, last updated on 6 May 2014
The study investigated the changes in DNA-methylation and gene expression during granulopoiesis. To this end CMP, GMP, PMC and PMN cell populations were isolated by FACS from bonemarrow from healty donors and analysed by CAGE as well as expression and DNA microarrays total RNA was isolated from CMP, GMP, PMC and PMN cells from human bonemarrow from 5 healty donors.
transcription profiling by array
Albin Sandelin, Andreas Lennartsson, Erik Arner, Hideya Kawaji, Hoof Ilka, Itoh Masayohi, Iyadh Douagi, Karl Ekwall, Michelle Rönnerblad, Mohsen Karimi, Piero Carninici, R R Forrest, Robin Andersson, Sayaka Nago-Sato, Sören Lehmann, Timo Lassmann, Tor Olofsson, Yoshihide Hayashizaki
Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation. Rï¿½nnerblad M, Andersson R, Olofsson T, Douagi I, Karimi M, Lehmann S, Hoof I, de Hoon M, Itoh M, Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Sandelin A, Ekwall K, Arner E, Lennartsson A, FANTOM consortium. , Europe PMC 24671952