E-GEOD-49431 - ChIP-seq for PRC2 components and H3K27me3 in E14 mouse embryonic stem cells
Released on 19 October 2013, last updated on 16 January 2014
This experiment sought to determine the chromatin structure and PRC2 occupancy at the promoters of all genes in mouse ESCs ChIP-seq for EZH2, SUZ12, and H3K27me3 were performed on WT E14 cells in 2 biological replicates each. In addition H3K27me3 ChIP-seq was also performed on a clone of E14 cells expressing a tagged version of EZH2, which for the purpose of this study was used as replicate #3.
Danny Reinberg, Roberto Bonasio, Syuzo Kaneko
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells. Kaneko S, Son J, Shen SS, Reinberg D, Bonasio R. , Europe PMC 24141703