E-GEOD-4911 - Transcription profiling of mouse pooled embryonic humeri E14.5 from wild type and RUNX2-/- mutants detects novel skeletogenesis target genes

Status
Released on 23 November 2007, last updated on 27 March 2012
Organism
Mus musculus
Samples (12)
Arrays (3)
Protocols (6)
Description
We used microarrays to identify genes differentially expressed between mouse RUNX2 -/- and wt embryonic humeri at stage E14.5 Experiment Overall Design: To minimize the effects of random biological variation, humeri from different preparations were pooled (approximately 75 wildtype and 60 Runx2-/- for each of the two biological replicates).
Experiment types
transcription profiling by array, co-expression, individual genetic characteristics
Contact
Citation
Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. J Hecht, V Seitz, M Urban, F Wagner, P N Robinson, A Stiege, C Dieterich, U Kornak, U Wilkening, N Brieske, C Zwingman, A Kidess, S Stricker, S Mundlos.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-4911.idf.txt
Sample and data relationshipE-GEOD-4911.sdrf.txt
Raw data (1)E-GEOD-4911.raw.1.zip
Processed data (1)E-GEOD-4911.processed.1.zip
Array designsA-AFFY-6.adf.txt, A-AFFY-7.adf.txt, A-AFFY-8.adf.txt
R ExpressionSetE-GEOD-4911.eSet.r
Links