E-GEOD-4911 - Transcription profiling of mouse pooled embryonic humeri E14.5 from wild type and RUNX2-/- mutants detects novel skeletogenesis target genes
Released on 23 November 2007, last updated on 27 March 2012
We used microarrays to identify genes differentially expressed between mouse RUNX2 -/- and wt embryonic humeri at stage E14.5 Experiment Overall Design: To minimize the effects of random biological variation, humeri from different preparations were pooled (approximately 75 wildtype and 60 Runx2-/- for each of the two biological replicates).
transcription profiling by array, co-expression, individual genetic characteristics
Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. J Hecht, V Seitz, M Urban, F Wagner, P N Robinson, A Stiege, C Dieterich, U Kornak, U Wilkening, N Brieske, C Zwingman, A Kidess, S Stricker, S Mundlos.