E-GEOD-48967 - Effects of FGF2 and cell culture surface on the transcriptome of adult human dermal fibroblasts

Status
Released on 15 October 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (24)
Array (1)
Protocols (7)
Description
The current study set to determine the effects of Fibroblast Growth Factor 2 and cell culture surface (tissue culture plastic and glass) on the transcriptome of adult human dermal fibroblasts. Transcriptional profiles of adult human dermal fibroblasts grown in four experimental conditions (glass, glass and addition of FGF2, plastic, plastic and addition of FGF2) were compared. Comparison of the transcriptomes will allow to identify significantly differentially expressed genes due to FGF2 and surface treatment, which in turn will allow for identification of the pathways affected by these factors in the human adult fibroblasts. Transcriptome analysis of adult human dermal fibroblasts grown on tissue culture plastic and glass, with and without 4ng/ml FGF2, was performed in two biological replicates and two technical replicates for each treatment condition.
Experiment type
transcription profiling by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-48967.idf.txt
Sample and data relationshipE-GEOD-48967.sdrf.txt
Raw data (1)E-GEOD-48967.raw.1.zip
Processed data (1)E-GEOD-48967.processed.1.zip
Array designA-GEOD-13693.adf.txt
Links