E-GEOD-481 - Transcription profiling of mouse allergen-induced goblet cells
Submitted on 27 June 2003, released on 13 June 2008, last updated on 10 June 2011
High numbers of goblet cells in airways contribute to the mucus obstruction characteristic of asthmatic airways. Allergen challenged mice exhibit robust expression of goblet cells within airway surface epithelium. This study looks at the temporal analysis of IL-13 exposed murine airways to elucidate pathways that result in differentiation of airway epithelial cells to goblet cells.
transcription profiling by array, compound treatment