E-GEOD-480 - Transcription profiling of mice treated with hypoxia and/or sleep fragmentation to investigate the hypothesis that intermittent hypoxia may lead to upregulation of some novel peptide(s) that have a powerful glucose lowering action
Submitted on 27 June 2003, released on 14 December 2007, last updated on 10 June 2011
This study examines the relationship between sleep apnea and glucose metabolism. Physiological studies have demonstrated that 5 days of exposure to intermittent hypoxia (similar to what occurs with sleep apnea) leads to significant improvements in glucose tolerance. Therefore, this study investigates the hypothesis that intermittent hypoxia may lead to upregulation of some novel peptide(s) that have a powerful glucose lowering action.
transcription profiling by array, co-expression, compound treatment, organism part comparison