E-GEOD-47697 - ETV4 promotes metastasis in response to combined activation of PI3kinase and RAS signaling in a mouse model of advanced prostate cancer

Status
Released on 23 July 2013, last updated on 3 June 2014
Organism
Mus musculus
Samples (21)
Array (1)
Protocols (6)
Description
Analysis of the transcriptome of mouse models of prostate cancer. NP (Nkx3.1CreERT2/+; Ptenfloxed/floxed) mice develop non-metastatic tumors while NPK (Nkx3.1CreERT2/+; Ptenfloxed/floxed; KrasG12D/+) mice develop metastatic tumors The NPK mice are also analyzed at early and late stages of tumorigenesis (1 vs. 3 months after induction) Total RNA obtained from prostate tumors of different genotypes and at different stages of dissease as indicated
Experiment type
transcription profiling by array 
Contacts
Antonina Mitrofanova <antonina@c2b2.columbia.edu>, Alvaro Aytes, Andrea Califano, Carolyn W Kinkade, Celine Lefebvre, Cory Abate-Shen, H C Le, Jason A Koutcher, Michael M Shen, Ming Lei, Robert D Cardiff, Vanessa Phelan
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-47697.idf.txt
Sample and data relationshipE-GEOD-47697.sdrf.txt
Processed data (1)E-GEOD-47697.processed.1.zip
Array designA-MEXP-1175.adf.txt
Links