E-GEOD-47598 - Activated T cell gene expression profile associated with Psoriasis

Status
Released on 2 December 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (24)
Array (1)
Protocols (7)
Description
Psoriasis is a Tcell-mediated disease characterized by the chronic inflammation of skin. Gene expression analyses on skin biopsies and freshly isolated PBMCs have provided important insights into Psoriasis pathophysiology. In the present study we analyze, for the first time, the gene expression profile of in vitro activated T cells in Psoriasis compared to normal heatlhy controls. T cells from PBMCs isolated from patients and healthy controls were in vitro activated with anti-CD3 and anti-CD28 for 72 hours. After T cell activation, cells were harvested and RNA extracted for microarray analysis.
Experiment type
transcription profiling by array 
Contacts
Toni Julià <toni.julia@vhir.org>, A Julià, C Ferrandiz, L Puig, N Palau, S Marsal
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-47598.idf.txt
Sample and data relationshipE-GEOD-47598.sdrf.txt
Processed data (1)E-GEOD-47598.processed.1.zip
Array designA-GEOD-10558.adf.txt
Links