E-GEOD-47553 - Effect of progerin on p53-deficient vascular smooth muscle cells

Status
Released on 22 September 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (8)
Array (1)
Protocols (7)
Description
Analysis of p53-deficient (E6-expressing) human vascular smooth muscle cells (VSMCs) that express progerin, a mutated form of lamin A resposible for Hutchinson- Gilford progeria syndrome (HGPS). p53 pathway is associated with HGPS. Results provide insight into molecular mechanisms underlying vascular dysfunction of HGPS caused by other than p53 pathway. The gene expression of VSMCs induced to express E6 and either lamin A or progerin by retroviral vectors.
Experiment type
transcription profiling by array 
Contacts
Daisuke Kinoshita <d.kinoopyg.0722@gmail.com>, Kazuhiro Sato, Masakatsu Yamashita
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-47553.idf.txt
Sample and data relationshipE-GEOD-47553.sdrf.txt
Raw data (1)E-GEOD-47553.raw.1.zip
Processed data (1)E-GEOD-47553.processed.1.zip
Array designA-GEOD-13497.adf.txt
Links