E-GEOD-4748 - Transcription profiling of human dendritic monocytes treated with LPS (lipopolysaccharide) or CyP (Cyanobacterial Product) reveals cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression

Status
Released on 26 October 2007, last updated on 3 June 2014
Organism
Homo sapiens
Samples (10)
Array (1)
Protocols (10)
Description
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. We report the identification and biologic characterization of an LPS-like molecule extracted from the cyanobacterium Oscillatoria Planktothrix FP1 (CyP).
Experiment types
transcription profiling by array, co-expression, compound treatment, in vitro, time series
Contacts
Citation
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. Annalisa Macagno, Monica Molteni, Andrea Rinaldi, Francesco Bertoni, Antonio Lanzavecchia, Carlo Rossetti, Federica Sallusto. , Europe PMC 16717116
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-4748.idf.txt
Sample and data relationshipE-GEOD-4748.sdrf.txt
Processed data (1)E-GEOD-4748.processed.1.zip
Array designA-AFFY-44.adf.txt
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