E-GEOD-47051 - Genome-wide differential gene expression signatures in pediatric acute lymphoblastic leukemia subtypes

Status
Released on 18 September 2013, last updated on 3 June 2014
Organism
Homo sapiens
Samples (108)
Array (1)
Protocols (7)
Description
We surveyed the genome-wide DNA methylation levels and gene expression patterns in patients with pediatric acute lymphoblastic leukemia. Using Affymetrix U133 Plus 2.0 GeneChips, we identified a relatively small set of CpG sites that are highly correlated with gene expression. Genome-wide expression analysis of 108 primary ALL samples by Affymetrix Human Genome U133 Plus 2.0 GeneChips used to investigate relationships between subtype-specific DNA methylation patterns and gene expression in 93 patients with both gene expression and DNA methylation data.
Experiment type
transcription profiling by array 
Contacts
Ann-Christine Syvänen, Jessica Nordlund
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-47051.idf.txt
Sample and data relationshipE-GEOD-47051.sdrf.txt
Processed data (1)E-GEOD-47051.processed.1.zip
Array designA-AFFY-44.adf.txt
Links