E-GEOD-4671 - Transcription profiling of mouse white adipose tissue from mice fed trans-10, cis-12 conjugated linoleic acid to determine the processes involved in the generated inflammation and de-lipidation of the adipose tissue
Submitted on 13 April 2006, released on 23 November 2007, last updated on 27 March 2012
The white adipose tissue (WAT) rapidly loses mass when mice are fed a diet containing trans-10, cis-12 conjugated linoleic acid (t10c12 CLA). A microarray analysis of WAT due to CLA feeding was performed to better define the processes and genes involved.
transcription profiling by array, co-expression, compound treatment, time series
Trans-10, cis-12 conjugated linoleic acid causes inflammation and delipidation of white adipose tissue in mice: a microarray and histological analysis. P Christopher LaRosa, Jess Miner, Yuannan Xia, You Zhou, Steve Kachman, Michael E Fromm. Physiol Genomics 27(3):282-94 (2006)