E-GEOD-46494 - Natural genetic variation perturbs collaborative transcription factor binding required for enhancer selection and function

Status
Released on 15 October 2013, last updated on 25 November 2013
Organism
Mus musculus
Samples (40)
Protocols (7)
Description
Natural genetic variation between two mouse strains was used as a natural mutagenesis screen to test various aspects of the proposed model for enhancer selection and function. Chromatin marks H3K4me2, H3K27Ac, and transcription factors PU.1, C/EBPa, and p65 were assessed by ChIP-Seq and GRO-Seq and RNA-Seq were used to measure gene expression in C57BL6/J and BALBc/J inbred mouse strains
Experiment types
ChIP-seq, RNA-seq of coding RNA 
Contacts
Citation
Effect of natural genetic variation on enhancer selection and function. Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, Glass CK. , Europe PMC 24121437
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-GEOD-46494.idf.txt
Sample and data relationshipE-GEOD-46494.sdrf.txt
Processed data (1)E-GEOD-46494.processed.1.zip
Links