E-GEOD-46239 - Transcription profiling by array of skin biopsies from dermatomyositis patients and healthy controls

Status
Released on 20 April 2013, last updated on 17 May 2016
Organism
Homo sapiens
Samples (52)
Array (1)
Protocols (6)
Description
The purpose of this study was to use global gene expression analysis to determine major functional pathways and genes dysregulated in the skin of active rashes of dermatomyositis patients. These data will be used to help assign a diagnosis to skin biopsies from patients with rashes that are not clearly dermatomyositis. In addition, we will correlate gene expression changes with specific histopathologic changes in skin biopsies that are taken adjacent to those analyzed for gene expression analysis. Finally, these data will be used to search for genes and pathways that are associated with clinical outcomes and autoantibody status in this cohort of patients. Gene expression profiling of healthy donor and dermatomyositis patient skin biopsy specimens.
Experiment type
transcription profiling by array 
Contact
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-46239.idf.txt
Sample and data relationshipE-GEOD-46239.sdrf.txt
Raw data (2)E-GEOD-46239.raw.1.zip, E-GEOD-46239.raw.2.zip
Processed data (1)E-GEOD-46239.processed.1.zip
Array designA-AFFY-44.adf.txt
Links