E-GEOD-46051 - Deep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence and absence of rotenone at 4 different time points

Status
Released on 16 April 2013, last updated on 25 April 2013
Organism
Caenorhabditis elegans
Samples (22)
Protocols (3)
Description
Background: We here show that inhibitors of mitochondrial complex I promote physical activity, stress resistance as well as lifespan of Caenorhabditis elegans despite normal food uptake, i.e. in the absence of DR. Dietary restriction (DR) extends lifespan and promotes metabolic health in evolutionary distinct species. The RNA-seq data comprises 4 age groups (1, 5, 10 and 20 days after L4) and 2 different conditions (rotenone and normal feeding (DMSO)) 22 samples: mRNA profiles of 1-day, 5-day and 10-day old worms as triplicates for each, rotenone and solvent control treatment; mRNA profiles of 20-day old worms as duplicates for each, rotenone and solvent control treatment
Experiment type
RNA-seq of coding RNA 
Contacts
Steffen Priebe <steffen.priebe@hki-jena.de>, Marco Groth, Matthias Platzer, Michael Ristow, Peter Hemmerich, Reinhard Guthke, Sebastian Schmeisser, Shamci  Monajembashi
MINSEQE
Exp. designProtocolsFactorsProcessedSeq. reads
Files
Investigation descriptionE-GEOD-46051.idf.txt
Sample and data relationshipE-GEOD-46051.sdrf.txt
Links