E-GEOD-46048 - High expression genes in urethane-induced lung tumor
Released on 16 April 2013, last updated on 3 June 2014
We estimated differences of urethane-induced tumors between Nrf2+/+ and Nrf2-/- ICR mouse. To identify Nrf2-regulated genes in tumors, we examined the mRNA expression profile both in tumor and non-tumor tissue of mouse 4 months after urethane administration. We performed microarray analyses using the comparable size of lung tumors (1.0 mm < tumor diameter < 1.5 mm) and intact non-tumor lung tissues derived either from Nrf2+/+ (n=8) or Nrf2–/–mice (n=8) at 16-weeks after urethane(1-g/kg body weight) treatment.
transcription profiling by array
Masayuki Yamamoto <email@example.com>, Hironori Satoh, Takashi Moriguchi