Standard Illumina scan protocol
The data were normalized by average signal on chip with Illumina BeadStudio (v.184.108.40.206).
ID_REF = VALUE = BeadStudio computed normalized signal intensity. Detection Pval =
Standard Illumina hybridization protocol
cRNA was labeled with biotin using Illumina TotalPrep RNA Amplification kit (Ambion)
The mice were treated with vehicle or S961 (10nMol/week) using Alzet osmotic pump for a week.
RNA was extracted with Trizol reagent, followed by clean-up and DNase I treatment with QIAGEN RNeasy mini kit in accordance with the prescribed protocol provided with the kit.