E-GEOD-45501 - Genome array of hair follicle genes in lamp skin with different patterns

Status
Released on 26 March 2013, last updated on 3 June 2014
Organism
Ovis aries
Samples (6)
Array (1)
Protocols (6)
Description
Differentially expressed genes in the skin tissue of newborn Hu sheep were screened using an Agilent gene chip and RT-PCR. Differential expression analysis revealed 3 groups of large waves and small waves; 1067, 2071, and 3879 differentially expressed genes; and 137 genes common to all 3 groups. Differentially expressed genes were classified using gene ontology. They were found to be mainly involved in cell differentiation, proliferation, apoptosis, growth, immune response, and ion transport. RT-PCR results of 4 differentially expressed genes were consistent with gene chip results. Combined with related literature, our results suggest that BMP7, MMP2, SNAI1, SFXN1, CDKNIC, MT3, and POU1F1 may have important effects on the formation of large-wave and small-wave hair follicles. The samples collected with three full-sib individual and they borned at two days, what's more they were from the same paternal, each pair of big wave and small wave individuals from the same female parent.
Experiment type
transcription profiling by array 
Contacts
nirong nirong <843208874@qq.com>, Hassan H Musa, J F Yin, J T Ding, L Chen, R Ni, W Sun
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-45501.idf.txt
Sample and data relationshipE-GEOD-45501.sdrf.txt
Raw data (1)E-GEOD-45501.raw.1.zip
Processed data (1)E-GEOD-45501.processed.1.zip
Array designA-GEOD-10778.adf.txt
Links