E-GEOD-45389 - Constitutively Active Foxo3 in Oocytes Preserves Ovarian Reserve in Mice

Status
Released on 8 June 2013, last updated on 2 June 2014
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (7)
Description
During female reproductive life, the reserve of ovarian follicles is reduced by maturation and atresia until menopause ensues. Foxo3 is required to maintain the ovarian reserve in mice. We asked if overexpression of a constitutively active FOXO3 protein can increase long-lasting ovarian reproductive capacity in mice. Trangenic vs non-transgenic mice onto Foxo3+/- vs Foxo3-/- genotype
Experiment type
transcription profiling by array 
Contacts
Citation
Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice. Pelosi E, Omari S, Michel M, Ding J, Amano T, Forabosco A, Schlessinger D, Ottolenghi C. , Europe PMC 23673628
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-45389.idf.txt
Sample and data relationshipE-GEOD-45389.sdrf.txt
Processed data (1)E-GEOD-45389.processed.1.zip
Array designA-MEXP-1175.adf.txt
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