E-GEOD-45304 - Transcriptional profiles of kidneys that underwent reversible UUO model using model mice for erythropoietin-deficiency anemia (ISAM)

Status
Released on 20 March 2013, last updated on 2 June 2014
Organism
Mus musculus
Samples (9)
Array (1)
Protocols (7)
Description
We have established a novel mouse model for postnatal erythropoietin (Epo)-deficiency anaemia, designated ISAM (inherited super anemic mouse) using a transgenic complementation rescue technique. To identify responsible signals for myofibroblastic transformation of Renal Erythropoietin-producing cells (REPs), we examined the mRNA expression profile of whole ISAM kidneys that underwent reversible UUO model. Unilateral ureteral obstruction (UUO)-induced gene expression changes were analyzed. Three UUO-treated samples (Clip), three reversed UUO kidneys (ClipR-14), and two sham-treated and one untreated samples were compared.
Experiment type
transcription profiling by array 
Contacts
Masayuki Yamamoto, Norio Suzuki, Shun Yamazaki, Takashi Moriguchi, Tomokazu Souma
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-45304.idf.txt
Sample and data relationshipE-GEOD-45304.sdrf.txt
Raw data (1)E-GEOD-45304.raw.1.zip
Processed data (1)E-GEOD-45304.processed.1.zip
Array designA-MEXP-724.adf.txt
Links