E-GEOD-4527 - Transcription profiling of human Th cells expressing Foxp3 and UBD ectopically
Released on 13 June 2008, last updated on 27 March 2012
Expression analysis revealed that UBD is a down-stream element of Foxp3 in human activated regulatory CD4+ T cells (Treg). Experiment Overall Design: Comparison of expression profiles measured in naturally occuring regulatory T-cells (Treg), Foxp3 and UBD transformed Th cells versus their controls with respect to the observed regulatory phenotype.
transcription profiling by array, unknown experiment type
UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells. Frank Ocklenburg, Darius Moharregh-Khiabani, Robert Geffers, Viktoria Janke, Susanne Pfoertner, Henk Garritsen, Lothar Groebe, Juergen Klempnauer, Kurt E J Dittmar, Siegfried Weiss, Jan Buer, Michael Probst-Kepper.