E-GEOD-45246 - miRNAs regulation by miR-145 in pancreatic cancer

Status
Released on 19 March 2013, last updated on 2 June 2014
Organism
Homo sapiens
Samples (4)
Array (1)
Protocols (8)
Description
miR-145 is a tumor suppressor miRNA in various malignancies including pancreatic cancer. How miR-145 regulates expression of other miRNAs could provide a panoramic view of the development of pancreatic cancer. Therefore, in this project, we aimed to characterize how other miRNAs are affected by miR-145 in hope for understanding proteomic changes that are not explained by miR-145 alone. miRNA microarray was used to compare expression of all miRNAs 48 hr after transfection of miR-145 mimics or control scramble RNA in a pancreatic cancer cell line, Mia-PaCa2.
Experiment type
transcription profiling by array 
Contacts
Tai-Chung Huang <huang@jhmi.edu>, Akhilesh Pandey, Tai C Huang, Yi Yang
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-45246.idf.txt
Sample and data relationshipE-GEOD-45246.sdrf.txt
Raw data (1)E-GEOD-45246.raw.1.zip
Processed data (1)E-GEOD-45246.processed.1.zip
Array designA-GEOD-13264.adf.txt
Links