E-GEOD-44706 - Coxsackievirus B3 (CVB3) infection of 129S1 and 129X1 (heart tissue day 6)

Status
Released on 1 April 2013, last updated on 2 June 2014
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (7)
Description
We infected two strains of mice, 129S1/SvImJ and 129X1/SvJ, with coxsackievirus type b3 (CVB3) at a dose of 500 pfu/g. 129S1 mice developed increased cardiopathology despite equal viral replication. We hypothesized that the increased cardiopathology might result from an ongoing pathologic host response that we could characterize by global expression profiling. Gene expression was assessed in hearts from 129S1 and 129X1 mice that were uninfected or infected for 6 days. Total RNA obtained from hearts of 3 129S1 and 3 129X1 that were infected or uninfected with CVB3(H3) at 500pfu/g and collected at day 6 post infection
Experiment type
transcription profiling by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-44706.idf.txt
Sample and data relationshipE-GEOD-44706.sdrf.txt
Processed data (1)E-GEOD-44706.processed.1.zip
Array designA-MEXP-1175.adf.txt
Links