E-GEOD-44692 - MiR-155 promotes blood-brain barrier dysfunction in neuroinflammation (part 1)

Status
Released on 29 April 2014, last updated on 2 June 2014
Organism
Homo sapiens
Samples (18)
Array (1)
Protocols (7)
Description
Here, we investigated the time-course changes in the pattern of microRNA (miRNA) expression of TNFα and IFNγ-stimulated and unstimulated hCMEC/D3 cells, an immortalized human cerebral microvascular endothelial cell line. In order to investigate pro-inflammatory cytokine-induced changes in miRNA levels in hCMEC/D3 cells, we challenged brain endothelial cells with TNFα and IFNγ (100 ng/ml) for 2 h, 6 h and 24 h and determined microRNA expression in cytokine-stimulated and unstimulated cells
Experiment type
transcription profiling by array 
Contacts
Miguel Alejandro Lopez-Ramirez <m.a.lopez-ramirez@yale.edu>, Arie Reijerkerk, Basil Sharrack, David Baker, David K Male, Dongsheng Wu, Gareth Pryce, Gregory J Michael, Helga E de Vries, Ignacio A Romero, Josh King-Robson, Julie E Simpson, Mark C Hirst, Miguel A Lopez-Ramirez, Oliver Kay
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-44692.idf.txt
Sample and data relationshipE-GEOD-44692.sdrf.txt
Raw data (1)E-GEOD-44692.raw.1.zip
Processed data (1)E-GEOD-44692.processed.1.zip
Array designA-GEOD-14767.adf.txt
Links