E-GEOD-44601 - Expression data from SND1 knockdown clones of human HCC cell line QGY-7703
Released on 1 April 2013, last updated on 2 June 2014
Staphylococcal nuclease domain-containing protein 1 (SND1) is overexpressed in human hepatocellular carcinoma (HCC) and positively regulates development and progression of HCC. We established stable clones expressing SND1 shRNA in QGY-7703 cells and analyzed the gene expression profiles of a control clone and two SND1 knockdown clones to check what genes are regulated by SND1. Steady-state proliferating cells were collected for RNA extraction and Affymetrix microarray hybridization. Three biological replicates each of a control clone and 2 SND1 knockdown clones.
transcription profiling by array
Devanand Sarkar, Myrna Serrano